Karloff bodies are best described as

Karloff bodies are best described as

• A. Lymphocytes with red staining granules
• B. Glandular epithelial cells
• C. Red blood cells with granules
• D. Platelets with granules

Answer: (A)

Karloff bodies are intracytoplasmic inclusions within lymphocytes that appear as red-staining (eosinophilic) granules on standard blood smear stains. This description—lymphocytes with red staining granules—best fits the characteristic feature of Karloff bodies. Red blood cells lack cytoplasmic granules, platelets are not lymphocytes and don’t present as granules inside lymphocytes, and glandular epithelial cells would look like epithelial cells, not discrete granules inside lymphocytes.

Karloff bodies are intracytoplasmic inclusions within lymphocytes that appear as red-staining (eosinophilic) granules on standard blood smear stains. This description—lymphocytes with red staining granules—best fits the characteristic feature of Karloff bodies. Red blood cells lack cytoplasmic granules, platelets are not lymphocytes and don’t present as granules inside lymphocytes, and glandular epithelial cells would look like epithelial cells, not discrete granules inside lymphocytes.